منابع مشابه
Maternal Risk Factors for Oral Clefts: A Case-Control Study
Introduction: A cleft lip with or without a cleft palate is one of the major congenital anomalies observed in newborns. This study explored the risk factors for oral clefts in Gorgan, Northern Iran. Materials and Methods: This hospital-based case-control study was performed in three hospitals in Gorgan, Northern Iran between April 2006 and December 2009. The case group contained 33 newborns...
متن کاملMaternal cigarette smoking during pregnancy and risk of oral clefts in newborns.
The results of previous epidemiologic research on the possible association between maternal smoking during pregnancy and risk of oral clefts in offspring have been inconsistent. This may be due in part to methodological limitations, including imprecise measurement of tobacco use, failure to consider etiologic heterogeneity among types of oral clefts, and confounding. This analysis, based on a l...
متن کاملOral clefts, maternal smoking, and TGFA: a meta-analysis of gene-environment interaction.
OBJECTIVE A meta-analysis was performed to examine the association among maternal cigarette smoking, infant genotype at the Taq1 site in the transforming growth factor alpha (TGFA) locus, and risk of nonsyndromic oral clefts, both cleft palate (CP) and cleft lip with or without cleft palate (CL/P). DESIGN Five published case-control studies were included in the meta-analyis. Pooled Mantel-Hae...
متن کاملTobacco smoking and oral clefts: a meta-analysis.
OBJECTIVE To examine the association between maternal smoking and non-syndromic orofacial clefts in infants. METHODS A meta-analysis of the association between maternal smoking during pregnancy was carried out using data from 24 case-control and cohort studies. FINDINGS Consistent, moderate and statistically significant associations were found between maternal smoking and cleft lip, with or...
متن کاملMaternal occupational exposure and oral clefts in offspring
BACKGROUND Previous studies suggest that periconceptional maternal occupational exposure to solvents and pesticides increase the risk of oral clefts in the offspring. Less is known about the effect of occupational exposure to metals, dust, and gases and fumes on development of oral clefts. METHODS This case-malformed control study used data from a population-based birth defects registry (Euro...
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ژورنال
عنوان ژورنال: Epidemiology
سال: 2008
ISSN: 1044-3983
DOI: 10.1097/ede.0b013e3181690731